Comprehensive Metabolic Profile (includes eGFR)
Blood Test for Fatigue and Metabolic Health
Recognize any of these?
This test is designed for people who suspect something is off but haven't had a clear answer. Each marker comes with a plain-English explanation, not just a number.
Symptom checker
Select any that apply — you'll see which markers in this panel are most relevant.
What this test measures
ALT
Elevated ALT levels can indicate liver damage, as ALT is an enzyme found primarily in the liver.
AST
High levels of AST can also indicate liver damage, as it is an enzyme that is often released when the liver is injured.
Albumin
Chronic CHF causes hypoalbuminemia through hepatic congestion impairing synthesis, intestinal edema reducing absorption, and cardiac cachexia. Low albumin (<3.5 g/dL) is an independent predictor of mortality and readmission in heart failure patients.
Albumin/Globulin Ratio
An abnormal albumin/globulin ratio can indicate liver disease. The liver produces albumin and globulin, so changes in their levels might point to liver dysfunction.
Alkaline Phosphatase
High levels of alkaline phosphatase can indicate liver disease or bone disorders, as this enzyme is produced in both the liver and bones.
Bilirubin, Total
Massive hepatocellular necrosis from acetaminophen overdose causes markedly elevated total bilirubin. Rising bilirubin indicates fulminant hepatic failure and poor prognosis.
Bun/Creatinine Ratio
A high BUN/Creatinine ratio can indicate conditions such as kidney disease or dehydration, as both BUN and creatinine are waste products filtered by the kidneys.
Calcium
Impaired kidney function disrupts calcium-phosphate homeostasis, typically causing hypocalcemia due to decreased vitamin D activation and phosphate retention. Calcium monitoring is crucial for CKD-mineral bone disorder management.
Carbon Dioxide
Low levels of carbon dioxide in the blood can indicate a metabolic disorder, such as metabolic acidosis, where the body produces too much acid or doesn't get rid of enough acid.
Chloride
Hyperchloremia frequently develops in AKI due to reduced renal chloride excretion and fluid resuscitation with chloride-rich solutions (0.9% saline). Chloride monitoring guides fluid management and helps assess renal recovery.
Creatinine
ATN from ischemia or nephrotoxins causes tubular cell death and kidney dysfunction, resulting in rapid creatinine elevation. Creatinine levels help diagnose ATN and monitor recovery of kidney function.
Globulin
High levels of globulin can indicate certain infections, autoimmune diseases, and blood disorders, as globulin proteins are part of the body's immune response.
Glucose
High levels of glucose can indicate diabetes, a chronic condition where the body's ability to process sugar is impaired.
Potassium
Acute adrenal insufficiency causes severe hyperkalemia with hyponatremia and hypoglycemia. Electrolyte pattern helps diagnose this life-threatening emergency requiring immediate corticosteroid replacement.
Protein, Total
Abnormally high levels of protein in urine can be indicative of kidney disease.
Sodium
Hyponatremia results from aldosterone deficiency causing renal sodium loss and cortisol deficiency impairing water excretion. Sodium is a key diagnostic marker in primary adrenal insufficiency.
Urea Nitrogen (Bun)
High levels of urea nitrogen (BUN) can indicate kidney disease or dehydration, as this waste product is filtered out of the blood by the kidneys.
eGFR
A low eGFR (estimated glomerular filtration rate) can indicate kidney disease, as this measures how well the kidneys are filtering waste from the blood.
Three steps from order to answer
Order online
Purchase securely on this page. Choose your nearest Quest Diagnostics draw site at checkout. Over 2,200 locations nationwide.
Takes about 2 minutes
Get your blood drawn
Book a time at your chosen location. A standard blood draw takes about 5 minutes. Your lab order is sent automatically when you purchase.
About 5 minutes at the lab
Review your results
Results arrive in your secure online portal in 1 to 2 business days. Each marker includes a plain-English explanation and reference range, not just a number.
Results in 1 to 2 business days
Results you can actually read.
Your results aren't just a number in a table. Each marker comes with a plain-English explanation and your result highlighted against the reference range. If anything falls outside normal, you'll see a note on what that typically means.
- Reference ranges shown for every marker
- Plain-English explanations, not medical jargon
- Downloadable as a PDF to share with your doctor
- Reviewed by a licensed physician before delivery
Results
what your report will look like
What makes this different from a standard doctor's visit
No doctor's visit required
All tests are physician-ordered on your behalf. You get clinical-grade diagnostics without a referral or prior appointment.
The same labs your doctor uses
Every blood draw is processed at Quest Diagnostics. The same facilities hospitals and clinics use nationwide. The science is identical. The experience is simpler.
Your results, your data
Results are private and belong to you. Download them, share with your own doctor, or keep them confidential. The choice is yours.
Physician-reviewed results
A licensed physician reviews your panel before results are released to you. If critical values are found, you'll be contacted directly.
Frequently asked questions
Text us at 863-270-9911 and we'll respond within a few hours.
No. When you purchase this test, a physician associated with our network reviews your order and issues the lab requisition on your behalf. You don't need a prior doctor's visit or referral.
This is a direct-pay test, priced to be accessible without insurance. Because you're paying directly, the cost is often lower than your insurance copay for a comparable physician-ordered panel. We provide an itemized receipt you can submit for HSA/FSA reimbursement.
The blood draw process and lab analysis are identical. Same CLIA-certified Quest Diagnostics facilities, same testing methodology. The difference is access. You order directly, skip the office visit, and get results faster.
A licensed physician reviews every panel before results are released. If any critical values are found, you'll receive a direct phone call before your results are posted. For out-of-range results that aren't critical, your results will include clear guidance on what the finding typically means and what next steps to consider.
Yes. Results are available as a PDF download from your portal. They're formatted in the standard lab report format your physician will recognize. Many people use these results to have a more informed conversation at their next appointment.
Your results are stored securely in a HIPAA-compliant system and are not shared with your insurance company, employer, or any third party without your explicit consent.