Most early miscarriages happen due to chromosomal abnormalities in the embryo that occur by chance. These random genetic errors become more common as maternal age increases, especially after age 35. However, recurrent miscarriage often has identifiable medical causes. Blood clotting disorders like antiphospholipid syndrome can cause clots in placental vessels, cutting off blood supply to the developing baby. Hormone imbalances, uterine abnormalities, cervical weakness, and thyroid disorders also increase risk.
Autoimmune conditions where the body produces antibodies against its own tissues can contribute to pregnancy loss. Uncontrolled diabetes, severe high blood pressure, and certain infections may also play a role. Lifestyle factors including smoking, heavy alcohol use, excessive caffeine, and severe stress can raise miscarriage risk. Advanced maternal age, previous miscarriages, and certain genetic conditions in either parent are additional risk factors to consider.